Liver of Frog Liver is the largest digestive gland in the body of frog. It is the reddish – brown structure present at the anterior region of the body cavity. Liver consists of two lobes in the body of frog. These two lobes are connected through the median bridge of liver tissue. Left lobe is larger then the right one so left lobe is further divided into two parts. So it looks like liver of frog consists 3 lobes. A thin walled, round, greenish sac like structure  known as gall bladder is present between the main lobes. Liver produces digestive juice known as bile which is necessary for digestion of fats. Bile is temporarily stored at gall bladder through their hepatic ducts. Cystic duct (duct of gall bladder) and hepatic duct combine to form common bile duct which runs through pancreas and joins with pancreatic duct and forms hepatopancreatic duct with opens to duodenum.

Histologically, liver consists of many lobules with are connected together by connective tissue. Each lobules consists of many polyhedral, cubical and glandular hepatic cells. Hepatic cells further consists of granular cytoplasm and droplets of fat and glycogens. Hepatic cells are arranged in column between the bile canals or canaliculi which unite to form bile ductules. Further bile ductules combine to form bile hepatic duct. These bile hepatic duct and cystic duct combine to form common bile duct. Hepatic cells produces bile and pours into bile duct.