They are:

1. it could not explain the active and bulk transport of materials through the cell membrane
2. it couldn't explain the transport of solute and solvent through the cell membrane
3. lipid: protein ratio does not favor this method
4. it does not explain the functional specificity and variability in the biomembranes.

cellular totipotency is the capacity of development of a whole body of organism from the living nucleated vegetative cell.

1. protein synthesis= ribosomes
2. photosynthesis= chloroplasts

Mitochondria are called the powerhouse of a cell as they release energy in the form of ATP (adenosine triphosphate).