It is written in my book that during Mitotic cell division replication of DNA takes place in S-phase of interphase resulting each chromosome with two sister chromatids. But formation of thick disti...
During the S-phase of interphase, DNA replication takes place within the entangled chromatin fibers. As a result of DNA replication, each chromosome in the cell is composed of two identical sister chromatids held together at the centromere.
During prophase of mitosis, the chromatin fibers condense and become visible as thick, distinct chromosomes. This condensation is necessary to ensure that the replicated chromosomes can be separated correctly during cell division. At this stage, the sister...