↪ Bioinorganic chemistry is an branch of chemistry that deals with the role of metal or compounds within biological and biochemical systems.
↪ Bioinorganic chemistry is a field that examines the roles of metals in biology.
↪ The scope of this branch, is amazingly a wide field as it explains the roles of different inorganic elements which are essential for life.
↪ It is important not only for chemists but also even for the biologists to understand the mechanisms of how biological system work.
⁕ It includes:
↪ The study of both natural phenomena such as the behavior of metalloproteins as well as artificially introduced metals (mix of biochemistry and inorganic chemistry).
↪ The study of naturally occurring inorganic elements in biochemical systems.
↪ The artificial introduction of metals into biological systems as probes to determine the function of biomolecules and as drugs to treat diseases.
↪ The investigation of inorganic elements in nutrition.
↪ The research on the toxicity of inorganic species ,etc.
Elements in Body
↪ It is interesting to know the content of the elements in a human body and the biological processes that the elements are performing in a healthy human body.
↪ If an average person weighing 70kg is considered, the elements that are present in the body are as follows:
|2.||Potassium and Sodium||105 + 13.5|
|4.||Iron + Zinc||4.5 + 3.0|
↪ The rest of other metals that are essential for the biological processes does not exceed one gram.
↪ From above data, we can see that the human body possesses the metal content that is essential for the biological processes are just only near 2%.
↪ But the dependencies of human life on these essential elements are far more than this figure in our hand.
↪ The following table illustrates the elements according to their action in the biological processes.
|Essential elements are absolutely for the continuation of life processes.||Traces elements are also important for the life process. Only their abundances are low.||Non essential elements are not essential for the life processes. If their abundance is zero, other elements serve similar function.||These elements are toxic in nature and give alteration on the natural functions of biological processes.|
|O, C, H, N, P, Na, K, Mg, Cl, Ca, S, etc.||I, Fe, Cu, Zn, Mn, Co, Mo, etc.||Al, Sr, Ba, Sn, etc.||As, Cd, Pb, Hg, etc.|